Anti-APPL1 Aptamer SELEX Service(Cat#: CTApt-2137)

This is an aptamer development services to screening aptamers binds to the APPL1 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target APPL1
Alternative Names Adaptor Protein, Phosphotyrosine Interacting With PH Domain And Leucine Zipper 1; DCC-Interacting Protein 13-Alpha; APPL; Adaptor Protein, Phosphotyrosine Interaction, PH Domain And Leucine Zipper Containing 1; Adapter Protein Containing PH Domain, PTB Domain And Leucine Zipper Motif 1; Dip13-Alpha; Adaptor Protein Containing PH Domain, PTB Domain And Leucine Zipper Motif 1; Signaling Adaptor Protein DIP13alpha; AKT2 Interactor; DIP13alpha; KIAA1428; MODY14; DIP13A; APPL1
Gene ID 26060
UniProt ID Q9UKG1
Target Overview The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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