This is an aptamer development services to screening aptamers binds to the AREL1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AREL1 |
| Alternative Names | Apoptosis Resistant E3 Ubiquitin Protein Ligase 1; KIAA0317; Apoptosis-Resistant HECT-Type E3 Ubiquitin Transferase 1; Apoptosis-Resistant E3 Ubiquitin Protein Ligase 1; Fibrosis-Inducing E3 Ligase 1; FIEL1; EC 2.3.2.26; AREL1 |
| Gene ID | 9870 |
| UniProt ID | O15033 |
| Target Overview | AREL1 (Apoptosis Resistant E3 Ubiquitin Protein Ligase 1) is a Protein Coding gene. Diseases associated with AREL1 include Colorectal Cancer, Hereditary Nonpolyposis, Type 7 and Lynch Syndrome. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin-protein transferase activity. An important paralog of this gene is HECW2. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |