This is an aptamer development services to screening aptamers binds to the ARF6 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ARF6 |
| Alternative Names | ADP Ribosylation Factor 6; ADP-Ribosylation Factor 6; ARF6 |
| Gene ID | 382 |
| UniProt ID | P62330 |
| Target Overview | This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |