This is an aptamer development services to screening aptamers binds to the ARHGAP23 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ARHGAP23 |
| Alternative Names | Rho GTPase Activating Protein 23; Rho-Type GTPase-Activating Protein 23; Rho GTPase-Activating Protein 23; KIAA1501; ARHGAP23 |
| Gene ID | 57636 |
| UniProt ID | Q9P227 |
| Target Overview | The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]). |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |