This is an aptamer development services to screening aptamers binds to the ARHGAP24 with an affinity of 1nM~1μM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Protein |
| Target | ARHGAP24 |
| Alternative Names | Rho GTPase Activating Protein 24; RAC1- And CDC42-Specific GTPase-Activating Protein Of 72 KDa; Rho GTPase-Activating Protein 24; Filamin-A-Associated RhoGAP; Sarcoma Antigen NY-SAR-88; RhoGAP Of 73 KDa; P73RhoGAP; RC-GAP72; FILGAP; FilGAP; Rho-Type GTPase-Activating Protein 24; DKFZP564B1162; ARHGAP2; FLJ33877; RCGAP72; P73 |
| Gene ID | 83478 |
| UniProt ID | Q8N264 |
| Target Overview | This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |