This is an aptamer development services to screening aptamers binds to the ARHGEF1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ARHGEF1 |
| Alternative Names | Rho Guanine Nucleotide Exchange Factor 1; Rho Guanine Nucleotide Exchange Factor (GEF) 1; 115 KDa Guanine Nucleotide Exchange Factor; P115-RHOGEF; P115RhoGEF; SUB1.5; LBCL2; 115-KD Protein; Lsc Homolog; P115-RhoGEF; ARHGEF1; Sub1.5; IMD62; GEF1; LSC |
| Gene ID | 9138 |
| UniProt ID | Q92888 |
| Target Overview | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |