Anti-ARHGEF11 Aptamer SELEX Service(Cat#: CTApt-2497)

This is an aptamer development services to screening aptamers binds to the ARHGEF11 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ARHGEF11
Alternative Names Rho Guanine Nucleotide Exchange Factor 11; Rho Guanine Nucleotide Exchange Factor (GEF) 11; PDZ-RHOGEF; KIAA0380; GTRAP48; Glutamate Transporter EAAT4-Associated Protein 48; RhoA-Specific Guanine Nucleotide Exchange Factor; Rho Guanine Exchange Factor (GEF) 11; RhoGEF Glutamate Transport Modulator; PDZ-RhoGEF; ARHGEF11
Gene ID 9826
UniProt ID O15085
Target Overview Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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