Anti-ARHGEF18 Aptamer SELEX Service(Cat#: CTApt-1279)

This is an aptamer development services to screening aptamers binds to the ARHGEF18 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ARHGEF18
Alternative Names Rho/Rac Guanine Nucleotide Exchange Factor 18; Rho/Rac Guanine Nucleotide Exchange Factor (GEF) 18; P114RhoGEF; 114 KDa Rho-Specific Guanine Nucleotide Exchange Factor; Rho-Specific Guanine Nucleotide Exchange Factor P114; Rho Guanine Nucleotide Exchange Factor 18; Septin-Associated RhoGEF; P114-RhoGEF; SA-RhoGEF; KIAA0521; P114-Rho-GEF; EC 3.4.24; ARHGEF18; MGC15913; EC 3.6.1; RP78
Gene ID 23370
UniProt ID Q6ZSZ5
Target Overview Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GEF family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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