Anti-ARHGEF9 Aptamer SELEX Service(Cat#: CTApt-1181)

This is an aptamer development services to screening aptamers binds to the ARHGEF9 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ARHGEF9
Alternative Names Cdc42 Guanine Nucleotide Exchange Factor 9; Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9; Rac/Cdc42 Guanine Nucleotide Exchange Factor 9; Rho Guanine Nucleotide Exchange Factor 9; PEM-2 Homolog; Collybistin; KIAA0424; PEM-2; HPEM-2 Collybistin; COLLYBISTIN; ARHGEF9; HPEM-2; ARHDH9; EIEE8; PEM2
Gene ID 23229
UniProt ID O43307
Target Overview The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. This brain-specific protein also acts as an adaptor protein for the recruitment of gephyrin and together these proteins facilitate receceptor recruitement in GABAnergic and glycinergic synapses. Defects in this gene are the cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy, as well as several other types of cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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