This is an aptamer development services to screening aptamers binds to the ARSA with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ARSA |
| Alternative Names | Arylsulfatase A; Cerebroside-Sulfatase; ASA; Epididymis Secretory Sperm Binding Protein; Metachromatic Leucodystrophy; EC 3.1.6.8; EC 3.1.6; ARSA; MLD |
| Gene ID | 410 |
| UniProt ID | P15289 |
| Target Overview | The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |