This is an aptamer development services to screening aptamers binds to the ARSB with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ARSB |
| Alternative Names | Arylsulfatase B; N-Acetylgalactosamine-4-Sulfatase; EC 3.1.6.12; ASB; G4S; MPS6; ARSB |
| Gene ID | 411 |
| UniProt ID | P15848 |
| Target Overview | Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targeted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |