Anti-ASIC2 Aptamer SELEX Service(Cat#: CTApt-1658)
This is an aptamer development services to screening aptamers binds to the ASIC2 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ASIC2 |
| Alternative Names |
Acid Sensing Ion Channel Subunit 2; Amiloride-Sensitive Cation Channel 1, Neuronal; BNaC1; BNC1; MDEG; Mammalian Degenerin Homolog; Acid-Sensing Ion Channel 2; Brain Sodium Channel 1; ASIC2a; HBNaC1; ACCN1; ACCN; Neuronal Amiloride-Sensitive Cation Channel 1; Amiloride-Sensitive Cation Channel Neuronal 1; Acid-Sensing (Proton-Gated) Ion Channel; Acid Sensing (Proton Gated) Ion Channel 2; Amiloride-Sensitive Brain Sodium Channel; Degenerin; ASIC2; BNAC1 |
| Gene ID |
40 |
| UniProt ID |
Q16515 |
| Target Overview |
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
