Anti-ASIC3 Aptamer SELEX Service(Cat#: CTApt-2517)
This is an aptamer development services to screening aptamers binds to the ASIC3 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ASIC3 |
| Alternative Names |
Acid Sensing Ion Channel Subunit 3; Testis Sodium Channel 1; Neuronal Amiloride-Sensitive Cation Channel 3; Amiloride-Sensitive Cation Channel 3, Testis; Acid-Sensing Ion Channel 3; DRASIC; SLNAC1; ACCN3; TNaC1; Acid-Sensing (Proton-Gated) Ion Channel 3; Acid Sensing (Proton Gated) Ion Channel ; Amiloride-Sensitive Cation Channel 3; Proton-Gated Cation Channel Subunit; Modulatory Subunit Of ASIC2a; HASIC3; HTNaC1; ASIC3; TNAC1 |
| Gene ID |
9311 |
| UniProt ID |
Q9UHC3 |
| Target Overview |
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
