Anti-ASPN Aptamer SELEX Service(Cat#: CTApt-2233)

This is an aptamer development services to screening aptamers binds to the ASPN with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ASPN
Alternative Names Asporin; PLAP-1; SLRR1C; Asporin (LRR Class 1) ; Asporin Proteoglycan; PLAP1; Periodontal Ligament Associated Protein 1; Periodontal Ligament-Associated Protein 1; Small Leucine-Rich Protein 1C; FLJ20129; ASPN; OS3
Gene ID 54829
UniProt ID Q9BXN1
Target Overview This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis, and also with intervertebral disc disease. Alternative splicing of this gene results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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