This is an aptamer development services to screening aptamers binds to the ATG4A with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ATG4A |
| Alternative Names | Autophagy Related 4A Cysteine Peptidase; Autophagy-Related Cysteine Endopeptidase 2; Autophagy-Related Protein 4 Homolog A; Cysteine Protease ATG4A; HAPG4A; APG4A; AUTL2; AUT-Like 2, Cysteine Endopeptidase (S. Cerevisiae ; ATG4 Autophagy Related 4 Homolog A (S. Cerevisiae) ; APG4 Autophagy 4 Homolog A (S. Cerevisiae) ; Autophagy Related 4A, Cysteine Peptidase; ATG4 Autophagy Related 4 Homolog ; AUT-Like 2, Cysteine Endopeptidase; AUT-Like 2 Cysteine Endopeptidase; APG4 Autophagy 4 Homolog A; Autophagin 2; Autophagin-2; EC 3.4.22.- ; EC 3.4.22; ATG4A |
| Gene ID | 115201 |
| UniProt ID | Q8WYN0 |
| Target Overview | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |