This is an aptamer development services to screening aptamers binds to the ATG4C with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ATG4C |
| Alternative Names | Autophagy Related 4C Cysteine Peptidase; AUTL3; Autophagy-Related Cysteine Endopeptidase 3; Autophagy-Related Protein 4 Homolog C; AUT-Like 3 Cysteine Endopeptidase; Cysteine Protease ATG4C; Autophagin-3; APG4C; AUTL1; AUT (S. Cerevisiae)-Like 1, Cysteine Endopeptidase; AUT-Like 1, Cysteine Endopeptidase (S. Cerevisiae) ; ATG4 Autophagy Related 4 Homolog C (S. Cerevisiae) ; APG4 Autophagy 4 Homolog C (S. Cerevisiae) ; Epididymis Secretory Sperm Binding Protein; Autophagy Related 4C, Cysteine Peptidase; ATG4 Autophagy Related 4 Homolog C; AUT-Like 1, Cysteine Endopeptidase; APG4 Autophagy 4 Homolog C; EC 3.4.22.- ; EC 3.4.22; FLJ14867; APG4-C; ATG4C |
| Gene ID | 84938 |
| UniProt ID | Q96DT6 |
| Target Overview | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |