Anti-ATG4D Aptamer SELEX Service(Cat#: CTApt-2253)

This is an aptamer development services to screening aptamers binds to the ATG4D with an affinity of 1nM~1μM.

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Certificate of Analysis Lookup

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Summary

Specifications
Target Category Protein
Target ATG4D
Alternative Names Autophagy Related 4D Cysteine Peptidase; Autophagy-Related Cysteine Endopeptidase 4; Autophagy-Related Protein 4 Homolog D; AUT-Like 4 Cysteine Endopeptidase; Cysteine Protease ATG4D; Autophagin-4; APG4-D; APG4D; AUTL4; AUT-Like 4, Cysteine Endopeptidase (S. Cerevisiae) ; ATG4 Autophagy Related 4 Homolog D (S. Cerevisiae) ; APG4 Autophagy 4 Homolog D (S. Cerevisiae) ; Autophagy Related 4D, Cysteine Peptidase; Cysteine Protease Involved In Autophagy; ATG4 Autophagy Related 4 Homolog D; APG4 Autophagy 4 Homolog D; EC 3.4.22.- ; EC 3.4.22; ATG4D
Gene ID 84971
UniProt ID Q86TL0
Target Overview Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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