This is an aptamer development services to screening aptamers binds to the ATG4D with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ATG4D |
| Alternative Names | Autophagy Related 4D Cysteine Peptidase; Autophagy-Related Cysteine Endopeptidase 4; Autophagy-Related Protein 4 Homolog D; AUT-Like 4 Cysteine Endopeptidase; Cysteine Protease ATG4D; Autophagin-4; APG4-D; APG4D; AUTL4; AUT-Like 4, Cysteine Endopeptidase (S. Cerevisiae) ; ATG4 Autophagy Related 4 Homolog D (S. Cerevisiae) ; APG4 Autophagy 4 Homolog D (S. Cerevisiae) ; Autophagy Related 4D, Cysteine Peptidase; Cysteine Protease Involved In Autophagy; ATG4 Autophagy Related 4 Homolog D; APG4 Autophagy 4 Homolog D; EC 3.4.22.- ; EC 3.4.22; ATG4D |
| Gene ID | 84971 |
| UniProt ID | Q86TL0 |
| Target Overview | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |