This is an aptamer development services to screening aptamers binds to the ATG5 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ATG5 |
| Alternative Names | Autophagy Related 5; ASP; Apoptosis-Specific Protein; Autophagy Protein 5; APG5L; HAPG5; APG5; ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) ; APG5 (Autophagy 5, S. Cerevisiae)-Like; APG5 Autophagy 5-Like (S. Cerevisiae) ; ATG5 Autophagy Related 5 Homolog; APG5 Autophagy 5-Like; APG5-LIKE; APG5-Like; SCAR25; ATG5 |
| Gene ID | 9474 |
| UniProt ID | Q9H1Y0 |
| Target Overview | The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |