Anti-ATN1 Aptamer SELEX Service(Cat#: CTApt-2441)

Name: Anti-ATN1 Aptamer SELEX Service
SKU: CTApt-2441
Rating: 5 (1 reviews)

This is an aptamer development services to screening aptamers binds to the ATN1 with an affinity of 1nM~1μM.

Certificate of Analysis Lookup

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Lot Number

Specifications

Target Category	Protein
Target	ATN1
Alternative Names	Atrophin 1; Dentatorubral-Pallidoluysian Atrophy Protein; Atrophin-1; D12S755E; DRPLA; B37; Dentatorubral-Pallidoluysian Atrophy (Atrophin-1) ; CHEDDA; ATN1; HRS; NOD
Gene ID	1822
UniProt ID	P54259
Target Overview	Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
Chemical Modification	N/A
Type	DNA
Length	20-80 nt
Affinity (Kd)	1nM~1μM
Binding Conditions/Buffer	PBS; buffer system with Serum; other