Anti-ATP1B1 Aptamer SELEX Service(Cat#: CTApt-2261)

This is an aptamer development services to screening aptamers binds to the ATP1B1 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ATP1B1
Alternative Names ATPase Na+/K+ Transporting Subunit Beta 1; Sodium/Potassium-Transporting ATPase Subunit Beta-1; Sodium-Potassium ATPase Subunit Beta 1 (Non-Catalytic) ; ATPase, Na+/K+ Transporting, Beta 1 Polypeptide; Sodium Pump Subunit Beta-1; ATP1B; Sodium/Potassium-Transporting ATPase Beta-1 Chain; Sodium/Potassium-Dependent ATPase Beta-1 Subunit; Sodium/Potassium-Dependent ATPase Subunit Beta-1; Beta 1-Subunit Of Na(+),K(+)-ATPase; Na, K-ATPase Beta-1 Polypeptide; Adenosinetriphosphatase; ATP1B1
Gene ID 481
UniProt ID P05026
Target Overview The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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