Anti-ATP6V1B2 Aptamer SELEX Service(Cat#: CTApt-2288)
This is an aptamer development services to screening aptamers binds to the ATP6V1B2 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ATP6V1B2 |
| Alternative Names |
ATPase H+ Transporting V1 Subunit B2; HO57; ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2; V-Type Proton ATPase Subunit B, Brain Isoform; Endomembrane Proton Pump 58 KDa Subunit; Vacuolar Proton Pump Subunit B 2; V-ATPase Subunit B 2; ATP6B2; VATB; VPP3; Vma2; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump), Beta Polypeptide, 56/58kD, Isoform 2; ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B, Isoform 2; Testicular Secretory Protein Li 65; H+ Transporting Two-Sector ATPase; Vacuolar H+-ATPase 56,000 Subuni; V-ATPase B2 Subunit; ATP6B1B; ATP6V1B2; DOOD; ZLS2 |
| Gene ID |
526 |
| UniProt ID |
P21281 |
| Target Overview |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
