Anti-ATP6V1F Aptamer SELEX Service(Cat#: CTApt-2293)
This is an aptamer development services to screening aptamers binds to the ATP6V1F with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ATP6V1F |
| Alternative Names |
ATPase H+ Transporting V1 Subunit F; ATP6S14; VATF; ATPase, H+ Transporting, Lysosomal 14kDa, V1 Subunit F; V-Type Proton ATPase Subunit F; Vacuolar Proton Pump Subunit F; V-ATPase 14 KDa Subunit; V-ATPase Subunit F; Vma7; H(+)-Transporting Two-Sector ATPase, 14kD Subunit; Adenosinetriphosphatase 14k Chain; Vacuolar ATP Synthase Subunit F; Vacuolar Proton Pump F Subunit; ATPase, Vacuolar, 14 KD; V-ATPase F Subunit; ATP6V1F |
| Gene ID |
9296 |
| UniProt ID |
Q16864 |
| Target Overview |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
