Anti-ATP7A Aptamer SELEX Service(Cat#: CTApt-2404)

This is an aptamer development services to screening aptamers binds to the ATP7A with an affinity of 1nM~1μM.

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Lot Number

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Summary

Specifications
Target Category Protein
Target ATP7A
Alternative Names ATPase Copper Transporting Alpha; Copper-Transporting ATPase 1; Copper Pump 1; ATPase, Cu++ Transporting, Alpha Polypeptide; Menkes Disease-Associated Protein; MNK; Cu++-Transporting P-Type ATPase; Menkes Syndrome; DSMAX; SMAX3; ATP7A; MC1; MK
Gene ID 538
UniProt ID Q04656
Target Overview This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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