Anti-AURKC Aptamer SELEX Service(Cat#: CTApt-2494)

This is an aptamer development services to screening aptamers binds to the AURKC with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target AURKC
Alternative Names Aurora Kinase C; ARK3; Serine/Threonine Kinase 13 (Aurora/IPL1-Like) ; Serine/Threonine-Protein Kinase Aurora-C; Serine/Threonine-Protein Kinase 13; Aurora/IPL1-Related Kinase 3; Aurora-Related Kinase 3; EC 2.7.11.1; Aurora 3; STK13; ARK-3; AIE2; AIK3; AurC; Epididymis Secretory Protein Li 90; Aurora/IPL1/EG2 Protein 2; Aurora/IPL1/Eg2 Protein 2; EC 2.7.11; HEL-S-90; Aurora-C; SPGF5; AURKC; AIRK3
Gene ID 6795
UniProt ID Q9UQB9
Target Overview This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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