This is an aptamer development services to screening aptamers binds to the AXL with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AXL |
| Alternative Names | AXL Receptor Tyrosine Kinase; UFO; Tyrosine-Protein Kinase Receptor UFO; AXL Oncogene; EC 2.7.10.1; JTK11; Tyro7; ARK; AXL Transforming Sequence/Gene; EC 2.7.10; AXL |
| Gene ID | 558 |
| UniProt ID | P30530 |
| Target Overview | The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |