Anti-AXL Aptamer SELEX Service(Cat#: CTApt-2308)

This is an aptamer development services to screening aptamers binds to the AXL with an affinity of 1nM~1μM.

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5’ Modification
 
3’ Modification
 
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Specifications
Target Category Protein
Target AXL
Alternative Names AXL Receptor Tyrosine Kinase; UFO; Tyrosine-Protein Kinase Receptor UFO; AXL Oncogene; EC 2.7.10.1; JTK11; Tyro7; ARK; AXL Transforming Sequence/Gene; EC 2.7.10; AXL
Gene ID 558
UniProt ID P30530
Target Overview The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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