Anti-B4GALT7 aptamer SELEX Service(Cat#: CTApt-1677)

This is an aptamer development services to screening aptamers binds to the B4GALT7 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target B4GALT7
Alternative Names Beta-1,4-Galactosyltransferase 7; Beta4Gal-T7; UDP-Galactose:Beta-N-Acetylglucosamine Beta-1,4-Galactosyltransferase 7; Proteoglycan UDP-Galactose:Beta-Xylose Beta1,4-Galactosyltransferase I; Xylosylprotein Beta 1,4-Galactosyltransferase, Polypeptide 7; UDP-Galactose:Beta-Xylose Beta-1,4-Galactosyltransferase; UDP-Gal:Beta-GlcNAc Beta-1,4-Galactosyltransferase 7; Xylosylprotein Beta-1,4-Galactosyltransferase; Xylosylprotein 4-Beta-Galactosyltransferase; Galactosyltransferase I; Beta-1,4-GalTase 7; XGALT1; XGPT; Beta-1,4-Galactosyltransferase VII; Beta4GalT-VII; EC 2.4.1.133; B4Gal-T7; EDSSPD1; B4GALT7; XGALT-1; XGalT-1; EDSSLA; EDSP1; XGPT1
Gene ID 11285
UniProt ID Q9UBV7
Target Overview This gene is a member of the beta-1,4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. Mutations in this gene have been associated with the progeroid form of Ehlers-Danlos syndrome.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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