Anti-BABAM2 aptamer SELEX Service(Cat#: CTApt-1794)

This is an aptamer development services to screening aptamers binds to the BABAM2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BABAM2
Alternative Names BRISC And BRCA1 A Complex Member 2; BRCC45; Brain And Reproductive Organ-Expressed (TNFRSF1A Modulator) ; Brain And Reproductive Organ-Expressed Protein; BRCA1/BRCA2-Containing Complex, Subunit 4; BRCA1/BRCA2-Containing Complex Subunit 45; BRISC And BRCA1-A Complex Member 2; BRCA1-A Complex Subunit BRE; BRCC4; BRE; BABAM2
Gene ID 9577
UniProt ID Q9NXR7
Target Overview This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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