This is an aptamer development services to screening aptamers binds to the BACH1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BACH1 |
| Alternative Names | BTB Domain And CNC Homolog 1; BTB And CNC Homology 1, Basic Leucine Zipper Transcription Factor 1; Transcription Regulator Protein BACH1; BACH-1; BTBD24; Basic Region Leucine Zipper Transcriptional Regulator BACH1; BTB And CNC Homolog 1; HA2303; BACH1 |
| Gene ID | 571 |
| UniProt ID | O14867 |
| Target Overview | This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |