Anti-BBC3 aptamer SELEX Service(Cat#: CTApt-1864)

This is an aptamer development services to screening aptamers binds to the BBC3 with an affinity of 1nM~1μM.

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Lot Number

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Summary

Specifications
Target Category Protein
Target BBC3
Alternative Names BCL2 Binding Component 3; PUMA; P53 Up-Regulated Modulator Of Apoptosis; P53-Upregulated Modulator Of Apoptosis; JFY-1; JFY1; Bcl-2-Binding Component 3, Isoforms 3/4; Bcl-2-Binding Component 3, Isoforms 1/2; Bcl-2-Binding Component 3; BBC3
Gene ID 27113
UniProt ID Q96PG8
Target Overview This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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