This is an aptamer development services to screening aptamers binds to the BBS5 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BBS5 |
| Alternative Names | Bardet-Biedl Syndrome 5; Bardet-Biedl Syndrome 5 Protein; DKFZp762I194; BBS5 |
| Gene ID | 129880 |
| UniProt ID | Q8N3I7 |
| Target Overview | This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is required for the formation of cilia. Alternate transcriptional splice variants have been observed but have not been fully characterized. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |