Anti-BCAT1 aptamer SELEX Service(Cat#: CTApt-1708)

This is an aptamer development services to screening aptamers binds to the BCAT1 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BCAT1
Alternative Names Branched Chain Amino Acid Transaminase 1; Branched-Chain-Amino-Acid Aminotransferase, Cytosolic; Branched Chain Aminotransferase 1, Cytosolic; EC 2.6.1.42; ECA39; BCT1; Branched Chain Amino-Acid Transaminase 1, Cytosolic; Placental Protein 18; Protein ECA39; PNAS121; BCAT(C) ; MECA39; BCATC; BCAT1; BCATc; PP18
Gene ID 586
UniProt ID P54687
Target Overview This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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