Anti-BCKDHB aptamer SELEX Service(Cat#: CTApt-1714)
This is an aptamer development services to screening aptamers binds to the BCKDHB with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
BCKDHB |
| Alternative Names |
Branched Chain Keto Acid Dehydrogenase E1 Subunit Beta; 2-Oxoisovalerate Dehydrogenase Subunit Beta, Mitochondrial; Branched-Chain Alpha-Keto Acid Dehydrogenase E1 Component Beta Chain; Branched Chain Keto Acid Dehydrogenase E1, Beta Polypeptide; BCKDH E1-Beta; EC 1.2.4.4; BCKDE1; Branched Chain Alpha-Ketoacid Dehydrogenase E1-Beta Subunit; Testis Secretory Sperm-Binding Protein Li 240m; E1b-Beta Subunit Of The Branched-Chain Complex; Maple Syrup Urine Disease; BCKDHB; E1B |
| Gene ID |
594 |
| UniProt ID |
P21953 |
| Target Overview |
This gene encodes the E1 beta subunit of branched-chain keto acid dehydrogenase, which is a multienzyme complex associated with the inner membrane of mitochondria. This enzyme complex functions in the catabolism of branched-chain amino acids. Mutations in this gene have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation and feeding problems. Alternative splicing at this locus results in multiple transcript variants. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
