Name: Anti-BCL2A1 aptamer SELEX Service
SKU: CTApt-1717
Rating: 5 (1 reviews)

Specifications

Target Category	Protein
Target	BCL2A1
Alternative Names	BCL2 Related Protein A1; BCL2L5; BFL1; GRS; Hemopoietic-Specific Early Response Protein; Bcl-2-Related Protein A1; Bcl-2-Like Protein 5; Protein BFL-1; Bcl2-L-5; ACC-1; ACC-2; HBPA1; ACC1; ACC2; Hematopoietic BCL2-Related Protein A1; Protein GRS; BCL2A1
Gene ID	597
UniProt ID	Q16548
Target Overview	This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Chemical Modification	N/A
Type	DNA
Length	20-80 nt
Affinity (Kd)	1nM~1μM
Binding Conditions/Buffer	PBS; buffer system with Serum; other

Anti-BCL2A1 aptamer SELEX Service(Cat#: CTApt-1717)

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