Anti-BCL2L12 aptamer SELEX Service(Cat#: CTApt-1720)

This is an aptamer development services to screening aptamers binds to the BCL2L12 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BCL2L12
Alternative Names BCL2 Like 12; BCL2-Like 12 (Proline Rich) ; Bcl-2-Like Protein 12; Bcl-2 Related Proline-Rich Protein; Bcl-2-Related Proline-Rich Protein; Bcl2-L-12; BCL2L12; BPR
Gene ID 83596
UniProt ID Q9HB09
Target Overview This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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