This is an aptamer development services to screening aptamers binds to the BCL7A with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BCL7A |
| Alternative Names | BAF Chromatin Remodeling Complex Subunit BCL7A; B-Cell CLL/Lymphoma 7 Protein Family Member A; BCL7A, BAF Complex Component; BCL Tumor Suppressor 7A; B-Cell CLL/Lymphoma 7A; B-Cell CLL/Lymphoma-7; BCL7A; BCL7 |
| Gene ID | 605 |
| UniProt ID | Q4VC05 |
| Target Overview | This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |