Anti-BCL7A aptamer SELEX Service(Cat#: CTApt-1921)

This is an aptamer development services to screening aptamers binds to the BCL7A with an affinity of 1nM~1μM.

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Lot Number

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Summary

Specifications
Target Category Protein
Target BCL7A
Alternative Names BAF Chromatin Remodeling Complex Subunit BCL7A; B-Cell CLL/Lymphoma 7 Protein Family Member A; BCL7A, BAF Complex Component; BCL Tumor Suppressor 7A; B-Cell CLL/Lymphoma 7A; B-Cell CLL/Lymphoma-7; BCL7A; BCL7
Gene ID 605
UniProt ID Q4VC05
Target Overview This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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