This is an aptamer development services to screening aptamers binds to the BCS1L with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BCS1L |
| Alternative Names | BCS1 Homolog, Ubiquinol-Cytochrome C Reductase Complex Chaperone; BC1 (Ubiquinol-Cytochrome C Reductase) Synthesis-Like; Mitochondrial Chaperone BCS1; BCS1-Like Protein; Hs.6719; H-BCS1; H-BCS; BCS1; BCS; BJS; Mitochondrial Complex III Assembly; BCS1 (Yeast Homolog)-Like; BCS1-Like (S. Cerevisiae ; Bjornstad Syndrom; BCS1-Like (Yeast) ; GRACILE Syndrome; GRACIL; MC3DN1; FLNM; BCS1L; PTD |
| Gene ID | 617 |
| UniProt ID | Q9Y276 |
| Target Overview | This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Several alternatively spliced transcripts encoding two different isoforms have been described. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |