Anti-BDKRB1 aptamer SELEX Service(Cat#: CTApt-1729)

This is an aptamer development services to screening aptamers binds to the BDKRB1 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BDKRB1
Alternative Names Bradykinin Receptor B1; B1 Bradykinin Receptor; BK-1 Receptor; BRADYB1; B1BKR; BKR1; B1R; Bradykinin B1 Receptor; Bradykinin Receptor 1; Bradyb1; BDKRB1; BKB1R
Gene ID 623
UniProt ID P46663
Target Overview Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The protein encoded by this gene belongs to the G-protein coupled receptor 1 family. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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