This is an aptamer development services to screening aptamers binds to the BDKRB2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BDKRB2 |
| Alternative Names | Bradykinin Receptor B2; B2 Bradykinin Receptor; BK-2 Receptor; BK-2; BKR2; B2R; BDKRB2; BRB2; BK2 |
| Gene ID | 624 |
| UniProt ID | P30411 |
| Target Overview | This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation, and binds to its kinin receptors, B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |