This is an aptamer development services to screening aptamers binds to the BEAN1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BEAN1 |
| Alternative Names | Brain Expressed Associated With NEDD4 1; Brain-Expressed Protein Associating With Nedd4 Homolog; Protein BEAN1; BEAN; Spinocerebellar Ataxia 31; SCA31; BEAN1 |
| Gene ID | 146227 |
| UniProt ID | Q3B7T3 |
| Target Overview | The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of>100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |