This product is an aptamer which binds to the Bevacizumab with an affinity of <200 nM.
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| Target Category | Antibody |
| Target | Bevacizumab |
| Alternative Names | N/A |
| Gene ID | N/A |
| UniProt ID | N/A |
| Target Overview | Bevacizumab is a humanized monoclonal antibody (mAb) against vascular endothelial growth factor A, and is used alone or with other drugs to treat metastatic colon cancer, lung cancer, renal cancer, ovarian cancer, and glioblastoma. |
| Chemical Modification | DNA |
| Length | 20-40 nt |
| Affinity (Kd) | <200 nM |
| Binding Conditions/Buffer | 50 mM phosphate buffer (pH 8.5) containing 1 mM EDTA to adjust the concentration to 1μM |
| GC Content | 58 |
| Molecular Weight | 7446.9 |
| Extinction Coefficient | 225500 |
| nmoles/OD260 | 4.067 |