Anti-BGN aptamer SELEX Service(Cat#: CTApt-1741)

This is an aptamer development services to screening aptamers binds to the BGN with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BGN
Alternative Names Biglycan; SLRR1A; DSPG1; PG-S1; Dermatan Sulphate Proteoglycan I; Bone/Cartilage Proteoglycan-I; Small Leucine-Rich Protein 1; Bone/Cartilage Proteoglycan I; Biglycan Proteoglycan; SEMD; MRLS; PGI; BGN
Gene ID 633
UniProt ID P21810
Target Overview This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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