This is an aptamer development services to screening aptamers binds to the BIK with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BIK |
| Alternative Names | BCL2 Interacting Killer; NBK; BCL2-Interacting Killer (Apoptosis-Inducing) ; Bcl-2-Interacting Killer; Apoptosis Inducer NBK; Natural Born Killer; BIP1; BP4; Apoptosis-Inducing NBK; BIK |
| Gene ID | 638 |
| UniProt ID | Q13323 |
| Target Overview | The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |