Anti-BIRC5 Aptamer SELEX Service(Cat#: CTApt-838)

This is an aptamer development services to screening aptamers binds to the BIRC5 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BIRC5
Alternative Names Baculoviral IAP Repeat Containing; Apoptosis Inhibitor 4; Baculoviral IAP Repeat-Containing Protein 5; Apoptosis Inhibitor Survivin; Survivin Variant 3 Alpha; EPR-1; API4; Baculoviral IAP Repeat-Containing 5; Survivin; BIRC5; IAP4
Gene ID 332
UniProt ID O15392
Target Overview This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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