Anti-BLMH aptamer SELEX Service(Cat#: CTApt-1751)

This is an aptamer development services to screening aptamers binds to the BLMH with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BLMH
Alternative Names Bleomycin Hydrolase; BH; BLM Hydrolase; EC 3.4.22.40; BMH; BLMH
Gene ID 642
UniProt ID Q13867
Target Overview Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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