Anti-BMF aptamer SELEX Service(Cat#: CTApt-1757)

Name: Anti-BMF aptamer SELEX Service
SKU: CTApt-1757
Rating: 5 (1 reviews)

This is an aptamer development services to screening aptamers binds to the BMF with an affinity of 1nM~1μM.

Certificate of Analysis Lookup

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Lot Number

Specifications

Target Category	Protein
Target	BMF
Alternative Names	Bcl2 Modifying Factor; Bcl-2-Modifying Factor; FLJ00065; BMF
Gene ID	90427
UniProt ID	Q96LC9
Target Overview	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Chemical Modification	N/A
Type	DNA
Length	20-80 nt
Affinity (Kd)	1nM~1μM
Binding Conditions/Buffer	PBS; buffer system with Serum; other