Anti-BMI1 aptamer SELEX Service(Cat#: CTApt-1758)
This is an aptamer development services to screening aptamers binds to the BMI1 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
BMI1 |
| Alternative Names |
BMI1 Proto-Oncogene, Polycomb Ring Finger; RNF51; Polycomb Group RING Finger Protein 4; Polycomb Complex Protein BMI-1; PCGF4; B Lymphoma Mo-MLV Insertion Region 1 Homolog (Mouse) ; Murine Leukemia Viral (Bmi-1) Oncogene Homolo; B Lymphoma Mo-MLV Insertion Region 1 Homolog; BMI1 Polycomb Ring Finger Proto-Oncogene; BMI1 Polycomb Ring Finger Oncogene; Polycomb Group Ring Finger 4; Polycomb Group Protein Bmi1; Ring Finger Protein 51; RING Finger Protein 51; Flvi-2/Bmi-; FLVI2/BMI1; BMI1 |
| Gene ID |
648 |
| UniProt ID |
P35226 |
| Target Overview |
This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
