Anti-BMP10 aptamer SELEX Service(Cat#: CTApt-1759)

This is an aptamer development services to screening aptamers binds to the BMP10 with an affinity of 1nM~1μM.

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3’ Modification
 
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Certificate of Analysis Lookup

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Lot Number

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Summary

Specifications
Target Category Protein
Target BMP10
Alternative Names Bone Morphogenetic Protein 10; BMP-10; BMP10
Gene ID 27302
UniProt ID O95393
Target Overview This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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