Anti-BMP4 aptamer SELEX Service(Cat#: CTApt-1763)

This is an aptamer development services to screening aptamers binds to the BMP4 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BMP4
Alternative Names Bone Morphogenetic Protein 4; Bone Morphogenetic Protein 2B; BMP2B; BMP2B; MCOPS6; BMP-2B; OFC11; BMP-; ZYME; BMP4; DVR4
Gene ID 652
UniProt ID P12644
Target Overview This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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