Anti-BMP5 aptamer SELEX Service(Cat#: CTApt-1764)

This is an aptamer development services to screening aptamers binds to the BMP5 with an affinity of 1nM~1μM.

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Certificate of Analysis Lookup

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Lot Number

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Summary

Specifications
Target Category Protein
Target BMP5
Alternative Names Bone Morphogenetic Protein; BMP-5; BMP5
Gene ID 653
UniProt ID P22003
Target Overview This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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