This product is an aptamer which binds to the BoNT A Light Chain (BoNT/A-rLc) with an affinity of <50 nM.
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| Target Category | Protein |
| Target | BoNT A Light Chain (BoNT/A-rLc) |
| Chemical Modification | DNA |
| Length | 40-60 nt |
| Affinity (Kd) | <50 nM |
| Binding Conditions/Buffer | 1X Binding Buffer: 20 mM Hepes, 150 mM NaCl, 2 mM KCl, 2 mM MgCl2, 2mM CaCl2 (pH 7.4). |
| GC Content | 0.4667 |
| Molecular Weight | 18544.08 g/mole |
| Extinction Coefficient | 547900 L/(mole·cm) |
| nmoles/OD260 | 1.83 |
Improved safety profileExcellentCompared to traditional detection methods, this aptamer offered a safer alternative. It reduced the risk associated with handling live toxins, making our lab procedures safer.
A vital tool in our labExcellentIt helped me identify trace amounts of Botulinum neurotoxin type A, which was crucial for my research objectives.
The binding specificity and sensitivity were exceptionalExcellentUsing this aptamer for our experiments was a wise choice. It's not only cost-effective but also produced highly accurate results, enhancing the quality of our scientific work.